Ipakitine contains Calcium carbonate – has phosphate-binding properties. Dogs and cats with kidney chronic disease tend to retain Phosphate, as the kidneys cannot filtrate it way from the body. The problem with this is that the phosphate attracts calcium to bind to it. When phosphate than accumulate in the body it results in mobilisation of calcium particularly from bone. This may lead to weakness of the bones.

Chitosan – derived from chitin, Chitin is a natural substance, the main building material of exoskeletons of arthropods. Due to chitosan’s specific molecular properties, it acts as an absorbent in the intestines and thus lowers the absorption of certain substances that can be harmful to the kidneys, including phosphates and some uraemic toxins. Numerous studies have shown the benefits of phosphate reduction in cats and dogs suffering from kidney failure and it is now widely accepted that there is a direct link between the length and quality of life of a cat or dog with kidney failure and the amount of phosphates they get through their food.

The ingredients in Ipakitine act as phosphate binding agents and lower the absorption of phosphates from the intestines. Thus, in respect of phosphate restriction they can mimic or enhance the effects of a phosphate restricted food. There is also a reduction in the absorption of some uraemic toxins that can affect, appetite, oral and stomach irritation and ulcers and normal kidney function. Renal disease should be managed carefully, using more than one approach, such as diet modification, prescription medications and nutritional supplements.

Administration

1g / 5kg body weight twice daily (one level scoop measures 1g of powder), mixed with food, for up to 6 months initially. It is recommended that a clinical check up be performed every 6 months by a vet and a blood test should be conducted to evaluate for kidneys parameters and phosphate and calcium levels. Administration can be life-long. Allow free access to fresh water at all times.