Metacam (Meloxicam) is a member of the class of drugs known as NSAIDs (non-steroidal anti-inflammatory drugs), the same class as such common over-the-counter pain remedies as Ibuprofen, Paracitamol and Aspirin. Most NSAIDs cannot be used in pets due to unacceptable side effects:
· Stomach ulceration – even perforation and rupture of the stomach can occur. This is not only painful, but also life threatening.
· Platelet deactivation – platelets are the cells controlling the ability to clot blood and, as a general rule, it is preferable not to promote bleeding. We would prefer platelets to remain active and able to function should we need them.
· Decreased blood supply to the kidney – this could tip a borderline patient into kidney failure.
The veterinary profession has been in need of an NSAID that could effectively relieve pain without the above risks. The key appears to lie with the enzyme responsible for many inflammatory mediators. A different but related enzyme is responsible for producing important biochemicals needed to maintain normal blood supply to the kidneys and Gastro Intestinal tract. It had been previously impossible to inhibit this enzyme, hence the side effects of previous NSAIDS.
This new ability to inhibit a specific proved to be revolutionary for pain management not only for pets but for humans as well. It has reduced stomach and intestinal side effects by 50% in humans and has made approval of NSAIDs possible for pets. Continue reading

